Figure 3.

Inhibition of late but not early gene expression by DRB is accompanied by a delay of HSV-1 DNA replication. a, time course of HSV-1 gene expression at 37 °C with an m.o.i. of 1 was examined with immunoblot. Experiments were performed in the presence or absence of 25 μm DRB. b, gene expression was quantified in the immunoblot. The mean value of two independent experiments is displayed. c, HSV-1 DNA replication was measured by qPCR in three independent experiments. The error bars show the standard deviation.