Figure 5.

ILEI dimers increase in vitro invasive capability of EpRas cells in a dose-dependent manner. Trans-well invasion assay of EpRas cells treated with increasing concentrations of recombinant mC3 ILEI dimers and monomers toward a 10% FCS attractant. Invasion was performed for 24 h and is shown as -fold change over non-treated control (ctrl). Recombinant human TGF-β1 (hTGFb1) treatment under the same conditions was used as positive control. Data represent the mean ± S.E. of three independent experiments. Statistical significance (*, p ≤ 0.05, *** p ≤ 0.001) as determined by an unpaired two-sided Student's t test.