Modelling the drivers of the spread of Plasmodium falciparum hrp2 gene deletions in sub-Saharan Africa

. 2017 Aug 24;6:e25008. doi: 10.7554/eLife.25008

Process	Transition	Hazard
Infection	S → I	$Λ_{i} (t - d_{E})$
Progression of untreated disease to asymptomatic infection	D → A	$r_{D} = \frac{1}{d_{D}}$
Progression of asymptomatic infection to subpatent infection	A → U	$r_{A} = \frac{1}{d_{A}}$
Progression of subpatent infection to susceptible	U → S	$r_{U} = \frac{1}{d_{U}}$
Progression of treated disease to uninfected prophylactic period	T → P	$r_{T} = \frac{1}{d_{T}}$
Progression from uninfected prophylactic period to susceptible	P → S	$r_{P} = \frac{1}{d_{P}}$
Super-infection from untreated clinical disease, asymptomatic infection or subpatent infection	D → I A → I U → I	$Λ_{i} (t - d_{E})$