Table 1.

Comparison of false-negative probabilities for LD and HIV testing: clinical samples

	LD testing (test dependence 0.63)				HIV disease testing (test dependence 0.950)				False negative ratio
	Test sensitivity		Probability of a false-negative result		Test sensitivity		Probability of a false-negative result		Two-tier LD and two-stage HIV	Two-tier LD and single HIV test
LD stage	First-tier test	Second-tier test	First-tier test	Second-tier test	First stage	Second stage	Single-stage HIV test	Second-stage HIV test
Acute	20.4%	21.2%	79.6%	85.6%	98.6%	98.6%	1.40%	1.33%	64	61
Early intermediate	30.4%	31.5%	69.6%	77.3%	98.9%	98.9%	1.10%	1.05%	74	70
Convalescent	37.2%	38.6%	62.8%	71.3%	99.4%	99.4%	0.60%	0.57%	125	119
Late intermediate	45.5%	47.3%	54.5%	63.3%	99.7%	99.7%	0.30%	0.29%	222	211
Neuro/arthritis	53.1%	55.2%	46.9%	55.7%	99.9%	99.9%	0.100%	0.095%	586	557

Abbreviations: LD, Lyme disease; Neuro, neurological.