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. 2017 Sep 12;12:6787–6797. doi: 10.2147/IJN.S139246

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© 2017 Cui et al. This work is published and licensed by Dove Medical Press Limited

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In vivo fluorescent imaging and biodistribution.

Notes: In vivo optical images (A) of nude mice bearing subcutaneous PC-3 tumor xenografts after intravenous injection of Gd₂O₃-FI-PEG-BBN or Gd₂O₃-FI-PEG. Ex vivo fluorescence images (B) of dissected organs from mice bearing PC-3 tumors sacrificed after injecting Gd₂O₃-FI-PEG-BBN. Quantitative fluorescent intensities of isolated tumors and main organs (C).

Abbreviations: BBN, bombesin; FI, 5(6)-carboxyfluorescein; Gd₂O₃, gadolinium oxide; PEG, polyethylene glycol.