Table 3.
Effects of methanolic leaf extracts of the plants on glucose levels and lipid profiles in progesterone-induced obese mice.
| Treatment | Biochemical Parameters | ||||
|---|---|---|---|---|---|
| Glucose | TG | TC | HDL-C | LDL-C | |
| Normal | 5.12 ± 0.27a | 0.74 ± 0.11a | 1.08 ± 0.16a | 0.52 ± 0.19a | 0.22 ± 0.03a |
| Progesterone (10 mg/kgbw) | 6.58 ± 0.28a | 1.00 ± 0.2a | 1.78 ± 0.36a | 0.54 ± 0.22a | 0.40 ± 0.08a |
| Orlistat (10 mg/kgbw) | 5.54 ± 0.30a | 0.92 ± 0.08a | 1.50 ± 0.15a | 0.60 ± 0.07a | 0.42 ± 0.15a |
| A. dubius (200 mg/kg/bw) | 6.32 ± 0.76a | 0.96 ± 0.07a | 1.50 ± 0.09a | 0.60 ± 0.07a | 0.54 ± 0.14a |
| A. dubius (400 mg/kg/bw) | 5.20 ± 0.22a | 0.72 ± 0.10a | 1.78 ± 0.22a | 0.74 ± 0.24a | 0.40 ± 0.04a |
| C. pepo (200 mg/kg/bw) | 5.80 ± 0.19a | 1.00 ± 0.06a | 1.08 ± 0.08a | 0.58 ± 0.16a | 0.22 ± 0.03a |
| C. pepo (400 mg/kg/bw) | 5.78 ± 0.97a | 0.94 ± 0.04a | 1.24 ± 0.16a | 0.54 ± 0.09a | 0.28 ± 0.02a |
| V. unguiculata (200 mg/kg/bw) | 5.52 ± 0.56a | 0.88 ± 0.05a | 1.36 ± 0.04a | 0.60 ± 0.00a | 0.62 ± 0.15a |
| V. unguiculata (400 mg/kg/bw) | 5.32 ± 0.17a | 0.82 ± 0.06a | 1.28 ± 1.02a | 0.62 ± 0.03a | 0.26 ± 0.05a |
Values expressed as Mean ± SEM for five animals per group. Statistical comparisons were made within a column and values with the same superscript letter are not significantly different by one-way ANOVA followed by Tukey's post hoc test (p > 0.05).