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. 2017 Sep 18;12(9):e0184646. doi: 10.1371/journal.pone.0184646

Table 2. Demographic and baseline characteristics of the patients by sICH per ECASS II criteria.

variables sICH (N = 44) Non-sICH(N = 1084) p
Age (year) 66.73±9.04 63.35±11.41 0.0918
 <70 22(50.00) 689(63.56) 0.0677
 ≧70 22(50.00) 395(36.44)
Gender (male) 24(54.55) 664(61.25) 0.3711
Hypertension 28(63.64) 639(58.95) 0.5352
Diabetes 9(20.45) 187(17.25) 0.5825
mRS 0–2 before stroke 44(100.00) 1062(97.97) 0.3399
NIHSS on admission 15(12–20.00) 11(7–16) 0.0002
 0–14 21(47.73) 749(69.10) 0.0041
 15–20 13(29.55) 228(21.03)
 >20 10(22.73) 107(9.87)
SBP on admission (mm Hg) 146.48±17.92 148.09±21.07 0.5893
DBP on admission (mm Hg) 87.00±11.56 85.90±12.69 0.7532
Serum glucose on admission (mmol/L) 8.88±3.81 7.67±2.99 0.0150
 ≦9.0 28(63.64) 880(81.18) 0.0040
 >9.0 16(36.36) 204(18.82)
Preexisting antihypertensive treatment 17(38.64) 415(38.28) 0.9624
Preexisting anticoagulant treatment 0(0.00) 19(1.75) 0.3758
Preexisting antiplatelet treatment 10(22.73) 148(13.65) 0.0891
Early infarct signs on admission CT head scan 2(4.55) 59(5.44) 1.0000
Hyper dense middle cerebral artery sign on admission CT 5(11.36) 72(6.64) 0.3615
Alteplase dose (mg/kg body weight) 0.90(0.80–0.90) 0.90(0.86–0.90) 0.0482
Onset to needle time (hours) 2.88(2.41–3.55) 2.83(2.33–3.25) 0.2754
Onset to needle time >3 h 20(45.45) 354(32.66) 0.0771
Stroke subtype
Large-artery atherosclerosis 15(34.09) 591(54.52) <.0001
Small-vessel occlusion 0(0.00) 117(10.79)
Cardioembolism 23(52.27) 198(18.27)
Other 6(13.64) 178(16.42)

Continuous variables: median with interquartile range (IQR) and P values per the Mann-Whitney U test. Categorical variables: proportions (%) and P values per the Pearson χ2 test.

age; ECASS II, the European Cooperative Acute Strokage; ECASS II, the European Cooperative Acute Stroke Study II; NIHSS, National Institutes of Health Stroke Scale; BP, blood pressure; mRS, modified Rankin Scale