Table 3. Demographic and baseline characteristics of the patients by sICH per NINDS criteria.
| variables | sICH (N = 61) | Non-sICH(N = 1067) | p |
|---|---|---|---|
| Age (year) | 67.18±9.28 | 63.27±11.42 | 0.0126 |
| <70 | 28(45.90) | 683(64.01) | 0.0044 |
| ≧70 | 33(54.10) | 384(35.99) | |
| Gender (male) | 32(52.46) | 656(61.48) | 0.1600 |
| Hypertension | 37(60.66) | 630(59.04) | 0.8033 |
| Diabetes | 10(16.39) | 186(17.43) | 0.8351 |
| mRS 0–2 before stroke | 61(100.00) | 1045(97.94) | 0.2574 |
| NIHSS on admission | 16(12–20) | 11(7–16) | <.0001 |
| 0–14 | 27(44.26) | 743(69.63) | <.0001 |
| 15–20 | 19(31.15) | 222(20.81) | |
| >20 | 15(24.59) | 102(9.56) | |
| SBP on admission (mm Hg) | 148.10±18.21 | 148.03±21.11 | 0.9850 |
| DBP on admission (mm Hg) | 87.07±10.99 | 85.88±12.73 | 0.5413 |
| Serum glucose on admission (mmol/L) | 8.35±3.47 | 7.68±3.00 | 0.1114 |
| ≦9.0 | 43(70.49) | 865(81.07) | 0.0426 |
| >9.0 | 18(29.51) | 202(18.93) | |
| Preexisting antihypertensive treatment | 22(36.07) | 410(38.43) | 0.7123 |
| Preexisting anticoagulant treatment | 0(0.00) | 19(1.78) | 0.2932 |
| Preexisting antiplatelet treatment | 11(18.03) | 147(13.78) | 0.3516 |
| Early infarct signs on admission CT head scan | 3(4.92) | 58(5.44) | 1.0000 |
| Hyper dense middle cerebral artery sign on admission CT | 8(13.11) | 69(6.47) | 0.0816 |
| Alteplase dose (mg/kg body weight) | 0.90(0.83–0.90) | 0.90(0.86–0.90) | 0.3226 |
| Onset to needle time (hours) | 2.75(2.38–3.33) | 2.83(2.33–3.25) | 0.8085 |
| Onset to needle time >3 h | 21(34.43) | 353(33.08) | 0.8285 |
| Stroke subtype | |||
| Large-artery atherosclerosis | 27(44.26) | 579(54.26) | <.0001 |
| Small-vessel occlusion | 0(0.00) | 117(10.97) | |
| Cardioembolism | 27(44.26) | 194(18.18) | |
| Other | 7(11.48) | 177(16.59) |
Continuous variables: median with inter quartile range (IQR) and P values per the Mann-Whitney U test. Categorical variables: proportions (%) and P values per the Pearson χ2 test.
The sICH indicates symptomatic intracranial hemorrhage; NINDS, the National Institute of Neurological Disorders and Stroke; NIHSS, National Institutes of Health Stroke Scale; BP, blood pressure; mRS, modified Rankin Scale