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. 2017 Sep 18;12(9):e0184646. doi: 10.1371/journal.pone.0184646

Table 4. Results of multivariate logistic regression analysis of sICH risk factors per mSITS-MOST,ECASS II or NINDS.

sICH per mSITS-MOST sICH per ECASS II sICH per NINDS
Adjusted OR(95%CI) p Adjusted OR(95%CI) p Adjusted OR(95%CI) p
Age≧70year 1.73(1.02–2.95) 0.04
Diabetes 3.50(1.34–9.16) 0.01
Serum glucose on admission >9.0mmol/L 2.84(1.48–5.46) 0.002
NIHSS on admission
 0–14 ref ref
 15–20 2.37(0.83–6.76) 0.11 1.54(0.82–2.90) 0.18
 >20 5.06(1.68–15.20) 0.004 2.81(1.42–5.57) 0.003
Stroke subtype
 Large-artery atherosclerosis ref ref ref
 Small-vessel occlusion NA - NA - NA -
 Cardioembolism 7.09(2.41–20.87) <0.001 4.99(2.53–9.84) <0.001 2.47(1.39–4.39) 0.002
 Other 5.12(1.40–18.72) 0.01 1.46(0.56–3.85) 0.44 0.99(0.42–2.32) 0.97

Multivariate logistic regression analysis adopted backward method. Ref, reference; N/A, not available or unreported

The sICH indicates symptomatic intracranial hemorrhage; SITS-MOST, Safe Implementation of Thrombolysis in Stroke-Monitoring Study; ECASS II, the European Cooperative Acute Stroke Study II; NINDS, the National Institute of Neurological Disorders and Stroke; NIHSS, National Institutes of Health Stroke Scale; BP, blood pressure; mRS, modified Rankin Scale