Table 6.
Cytogenetics and laboratory follow-up in 3 patients with discrepant findings
| At baseline | At PET/CT imaging | At FU BM | After consolidation | |||||
|---|---|---|---|---|---|---|---|---|
| 1 month | 4 months | 10 months | 16 months | |||||
| Pt 6 | Cytogenetics | 46, XX, t(8;21)(q22;q22)[19]/46,XX[1] | ||||||
| WBC (× 109/L) | 17.34 | 0.68 | 3.41 | 4.47 | 17.16 | –a | –a | |
| Hb (g/dL) | 7 | 9.6 | 10.8 | 11 | 13.2 | –a | –a | |
| Platelet (× 109/L) | 10 | 21 | 13 | 70 | 30 | –a | –a | |
| LDH (U/L) | 571 | 169 | 343 | 246 | 1041 | –a | –a | |
| Pt 7 | Cytogenetics | 43-45, XY, del(3)(p11.2), del(5)(q13q33),−7,+8,del(12)(p11.2p11.2), −21[cp20] | ||||||
| WBC (× 109/L) | 19.02 | 0.85 | 3.09 | 3.3 | 8.2 | –a | –a | |
| Hb (g/dL) | 4.6 | 9.1 | 7.7 | 9 | 9.4 | –a | –a | |
| Platelet (× 109/L) | 10 | 32 | 176 | 170 | 38 | –a | –a | |
| LDH (U/L) | 606 | 347 | 229 | 178 | 418 | –a | –a | |
| Pt 9 | Cytogenetics | 45,X,−Y, t(8;21)(q22;q22), add(14)(q32)[20] : RUNX1-RUNX1T1 | ||||||
| WBC (× 109/L) | 30.72 | 0.66 | 5.38 | 11.41 | 4.65 | 4.65 | 6.13 | |
| Hb (g/dL) | 3 | 10.3 | 12.5 | 10.5 | 13.7 | 15.4 | 15.2 | |
| Platelet (× 109/L) | 11 | 55 | 297 | 49 | 97 | 97 | 105 | |
| LDH (U/L) | 706 | 310 | 227 | 306 | 151 | 153 | 178 | |
Pt patient
aPatient 6 and 7 relapsed or were strongly suspected of relapse at 4 months after consolidation