Table 1.

Baseline characteristics of patients according to sedonalgesia status during NIPPV

	Sedation and/or analgesia (N = 41)	Non sedoanalgesia (N = 39)	P
Agec, years	68(54 ~ 78)	78(62 ~ 83)	0.077
Maleb	30 (73%)	25 (64%)	0.471
APACHE II at ICU admissiona, points	17.95 ± 6.87	19.28 ± 6.49	0.376
APACHEII at extubationa, points	10.61 ± 3.89	10.97 ± 5.29	0.725
NIPPV before mechanical ventilationb	11 (27%)	11(28%)	0.890
Diagnosis
Pneumoniab	24(59%)	25(64%)	0.610
AECOPDb	13(32%)	12(31%)	0.928
Otherb	4(10%)	2(5%)	0.676
Interface			0.476
Oral-nasal maskb	38(93%)	34(87%)
Nasal maskb	3(7%)	5(13%)
Before extubation
OIa	230.43 ± 62.33	260.59 ± 77.83	0.059
pHa	7.44 ± 0.03	7.44 ± 0.04	0.891
PaCO2 a, mmHg	50.46 ± 10.26	47.27 ± 11.43	0.193
body temperaturea	36.73 ± 0.38	36.91 ± 0.53	0.090
RRa, bpm	20.61 ± 4.69	22.59 ± 6.24	0.112
HRa, bpm	105.59 ± 15.78	101.36 ± 17.72	0.263
SBPa, mmHg	140.34 ± 22.69	136.92 ± 18.93	0.463
DBPa, mmHg	74.51 ± 13.16	73.41 ± 10.53	0.680
Half an hour after extubation
OIa	266.94 ± 325.79	225.47 ± 67.65	0.438
pHa	7.44 ± 0.05	7.43 ± 0.04	0.293
PaCO2 a, mmHg	50.34 ± 11.97	50.71 ± 13.53	0.897
RASS at start of NIPPV
-2 to −1 pointsb	15(37%)	3(8%)	0.003
0 to 2 pointsb	26(73%)	36(72%)
IPAPmaxa, cmH2O	13.00 ± 2.58	12.74 ± 2.28	0.639
EPAPmaxa, cmH2O	5.56 ± 0.95	5.44 ± 1.17	0.599

AECOPD acute exacerbation of chronic obstructive pulmonary disease, APACHE II The Acute Physiologic and Chronic Health Evaluation, DBP diastolic blood pressure, EPAP expiratory positive airway pressure, HR heart rate, IPAP inspiratory positive airway pressure, IQR interquartile range, OI oxygenation index, RASS Richmond Agitation Sedation Scale, RR respiratory rate, SBP systolic blood pressure, SD standard deviation

^aResults are expressed as mean ± SD

^bResults are expressed as n(%)

^cResults are expressed as median (IQR)