Table 4.
Population coverage analysis of the highest scoring 262 epitope set from 22 probable antigens and gold standard antigen LSA-3 of P. falciparum in the malaria-endemic regions
| Population selected | No. of optimized epitopes/candidate epitopes | No. of covered/target alleles | Locus coverage (%) | Population coverage (%) | ||
|---|---|---|---|---|---|---|
| A | B | C w | ||||
| Probable 22 antigens | ||||||
| NE Asia | 94/119 | 20/20 | 62.56 | 52.89 | 25.13 | 98.26 |
| SE Asia | 105/154 | 12/12 | 59.66 | 36.2 | 24.79 | 96.25 |
| SW Asia | 89/130 | 18/19 | 50.95 | 39.06 | 32.51 | 95.93 |
| SS Africa | 67/106 | 13/14 | 24.32 | 24.76 | 32.82 | 85.37 |
| LSA-3 | ||||||
| SS Africa | 4/12 | 7/14 | 13.65 | 18.89 | 14.48 | 64.12 |