Figure 4.

Longitudinal study of Aβ phagocytosis in the Mϕs of ω-3–supplemented patients. A) Mϕs isolated at 2 visits were treated with RvD1 or SMF/Res and exposed for 18 h to fluorescent Aβ. Comparison of mean phagocytosis by repeated measures ANOVA (not significant). B) Immunofluorescence of Mϕs (patient 14) exposed to fluorescent Aβ at baseline (blue) and after treatment by RvD1 or SMF/Res (red) for 18 h. C) Tunicamycin decreased phagocytosis of fluorescent Aβ. SMF/Res recovered phagocytosis. IOD, integrated optical density; MFI, mean fluorescence intensity. Error bars indicate sem.