Table 6.
E. meningoseptica | E. anophelis | E. miricola | ||||||
---|---|---|---|---|---|---|---|---|
Locus number | Gene in Em3 | Putative function | Em3 | 502 | R26 | NUHP1 | ATCC 33958 | EM_CHUV |
β-lactam | ||||||||
BFF93_RS01220 | bla GOB-13 | Class B carbapenemase BlaGOB-13 | + | + | + | + | + | + |
BFF93_RS04805 | – | β-lactamase | + | + | + | + | + | + |
BFF93_RS05700 | – | β-lactamase (EC 3.5.2.6) | + | + | + | + | + | + |
BFF93_RS07625 | bla ACME | β-lactamase (BlaACME) VEB-1-like | + | + | + | + | + | + |
BFF93_RS06860 | bla B | BJP β-lactamase | + | + | + | + | + | + |
BFF93_RS09265 | – | MBL fold metallo-hydrolase | + | + | + | + | + | + |
BFF93_RS06995 | – | β-lactamase (EC 3.5.2.6) | + | + | + | + | + | + |
BFF93_RS14540 | – | β-lactamase | + | + | + | + | – | + |
BFF93_RS12085 | – | β-lactamase (EC 3.5.2.6) | + | + | + | + | + | + |
BFF93_RS12510 | – | MBL fold metallo-hydrolase | + | + | + | + | + | + |
BFF93_RS14000 | blaB-9 | Class B carbapenemase BlaB-9 | + | + | + | + | + | + |
BFF93_RS01365 | – | β-lactamase (EC 3.5.2.6) | + | + | + | + | + | + |
Sulfonamide | ||||||||
BFF93_RS00125 | dhfR | Dihydrofolate reductase DHFR | + | + | + | + | + | + |
BFF93_RS17395 | – | Bifunctional deaminase-reductase | + | + | + | + | + | + |
BFF93_RS00125 | dhfR | Dihydrofolate reductase DHFR | + | + | + | + | + | + |
BFF93_RS17395 | – | Bifunctional deaminase-reductase protein | + | + | + | + | + | + |
BFF93_RS14765 | folP | Dihydropteroate synthase FolP (EC 2.5.1.15) | + | + | + | + | + | + |
Tetracycline | ||||||||
BFF93_RS08380 | tetA | Tetracycline efflux protein TetA | + | + | + | + | + | + |
BFF93_RS07335 | – | Transmembrane efflux protein | + | + | + | + | + | + |
BFF93_RS12745 | – | Antibiotic transporter | + | + | + | + | + | + |
Macrolide | ||||||||
BFF93_RS00370 | lolD | Macrolide resistance, ABC transporter | + | + | + | + | + | + |
BFF93_RS05670 | emrB | Erythromycin resistance, EmrB/QacA | + | + | – | – | + | + |
BFF93_RS05670 | emrB | Erythromycin resistance, EmrB/QacA | + | + | + | + | + | + |
BFF93_RS10830 | emrB | Erythromycin resistance, EmrB/QacA | + | + | + | + | + | + |
BFF93_RS03320 | – | Erythromycin esterase | + | + | + | + | + | + |
Quinolone | ||||||||
BFF93_RS04670 | gyrA | DNA gyrase GyrA subunit A (T83S) | + | + | + | + | + | + |
BFF93_RS09245 | gyrB | DNA gyrase GyrB subunit A (M437 L) | + | + | + | + | + | + |
BFF93_RS08895 | parE | DNA topoisomerase IV subunit B (M437F/A473L) | + | + | + | + | + | + |
Aminoglycoside | ||||||||
BFF93_RS10790 | ant-6 | Aminoglycoside 6-adenylyltransferase | + | + | + | + | + | + |
Chloramphenicol | ||||||||
BFF93_RS14765 | catB | Chloramphenicol acetyltransferase CatB | + | + | + | + | + | + |
BFF93_RS04080 | bcr/cflA | Bcr/CflA efflux pump | + | + | + | + | + | + |
“+” or “-” indicates the presence or absence of genes in the selected Elizabethkingia