Table 1.
Demographic characteristics of the healthy controls and OBI, ASC and CHB patients
| Variable | HC N = 117 |
OBI N = 119 |
ASC N = 107 |
CHB N = 115 |
χ2/F | P value | χ2/F | P valuea |
|---|---|---|---|---|---|---|---|---|
| Age (year) | 45.58 ± 13.08 | 42.30 ± 13.60 | 44.19 ± 15.00 | 44.40 ± 13.10 | 1.16 | 0.3246 | – | – |
| Gender (male) | Male:76 | Male:84 | Male:76 | Male:78 | 1.26 | 0.7380 | 0.27 | 0.602 |
| BMI (kg/m2) | 24.83 ± 3.04 | 24.48 ± 2.94 | 24.64 ± 4.50 | 24.38 ± 2.90 | 0.39 | 0.7629 | 0.39 | 0.763 |
| ALT (IU/L) | 22.35 ± 13.94 | 24.68 ± 11.33 | 28.42 ± 17.97 | 99.05 ± 69.47 | 115.24 | < .0001 | 115.87 | 0.000 |
| AST (IU/L) | 29.36 ± 13.81 | 28.31 ± 12.28 | 29.08 ± 14.47 | 115.52 ± 107.60 | 70.70 | < .0001 | 71.06 | 0.000 |
| Anti-HBs(positive) | Positive:64 | Positive:20 | Positive:25 | Positive:13 | 67.46 | < .0001 | 41.31 | 0.000 |
| WBC (109/L) | 5.03 ± 1.69 | 5.25 ± 1.92 | 4.97 ± 1.62 | 4.84 ± 1.78 | 1.13 | 0.3347 | 1.08 | 0.358 |
| LYM (109/L) | 34.11 ± 8.98 | 33.49 ± 9.28 | 34.86 ± 8.82 | 33.22 ± 9.62 | 0.70 | 0.5519 | 0.84 | 0.472 |
| HBV-DNA (IU/ML) | NDa | 2.43 ± 1.34 | 2.49 ± 2.14 | 4.20 ± 2.28 | 30.31 | < .0001 | 30.12 | 0.000 |
| Genotype | Type B(15) | Type B(15) | Type B(27) | |||||
| Type C(83) | Type C(88) | Type C(88) | ||||||
| Type B&C(3) | Type B&C(1) | |||||||
| NDa(18) | NDa(3) |
ND not detected, WBC white blood cell count, LYM lymphocyte count, HC healthy controls, OBI occult hepatitis B virus infection, ASC asymptomatic HBsAg carriers, CHB chronic hepatitis B
a P value was adjusted for age