Table 1.
Characteristic | MetS cases (n = 92) | Controls (n = 105) | p |
---|---|---|---|
Age, years, mean ± S.D | 45.33 ± 9.56 | 44.74 ± 9.67 | 0.672c |
BMI, Kg/m2, mean ± S.D | 37.64 ± 5.7 | 26.07 ± 5.4 | <0.001 a |
Waist (cm),mean ± S.D | 119.76 ± 10.96 | 89.68 ± 13.87 | <0.001 a |
TC (mg/dl), mean ± S.D | 182.12 ± 44.52 | 165.42 ± 22.74 | 0.001 a |
TAG (mg/dl), mean ± S.D | 177.45 ± 84.06 | 110.06 ± 33.25 | <0.001 a |
HDL-C (mg/dl), mean ± S.D | 38.51 ± 9.33 | 44.76 ± 8.07 | <0.001 a |
LDL-C (mg/dl), mean ± S.D | 108.11 ± 39.44 | 98.58 ± 20.31 | 0.038 a |
FPG (mg/dl), median(min-max) | 161(64-361) | 89(60-323) | <0.001 b |
FSI(μIU/mL), median(min-max) | 13.39(2.9–30.3) | 8.5(1-30) | <0.001 b |
HOMA-IR, median(min-max) | 4.48(0.77–20.46) | 1.9(0.2-23.93) | <0.001 b |
QUICKI, mean ± S.D | 0.31 ± 0.04 | 0.35 ± 0.05 | <0.001 a |
FTO (rs9939609) | |||
TT, n(%) | 24 (26.1) | 43 (41) | |
AT, n(%) | 50 (54.4) | 54 (51.4) | |
AA, n(%) | 18 (19.5) | 8 (7.6) | 0.014 c |
Values are mean ± SD for parametric variables or median (range) for non-parametric variables. BMI Body mass index, WC Waist circumference, T.C Total cholesterol, TAG Triacylglycerol, HDL-C High density lipoprotein-cholesterol, LDL-C Low density lipoprotein-cholesterol, FPG Fasting plasma glucose, FSI Fasting serum insulin
aIndependent T- test, two-sided p value >0.05 non-significant
bMann–Whitney U test, two sided p value >0.05 non-significant
cChi-square test, two-sided p value >0.05 non-significant