Fig. 3.
Determinants of attenuated microvascular function in those with diabetes (mean ± 95% CI), irrespective of cardiovascular disease status combined. a Peak endothelial dependent responses to acetylcholine (ACh) in those with and without diabetes adjusted for age and sex. b Peak endothelial independent response to sodium nitroprusside (SNP) in those with and without diabetes adjusted for age and sex. c Peak endothelial dependent responses to acetylcholine (ACh) in those with and without diabetes adjusted for age, sex and conventional cardiovascular risk factors (body mass index, mean arterial blood pressure, total cholesterol and smoking status). d Peak endothelial independent response to sodium nitroprusside (SNP) in those with and without diabetes adjusted for age, sex and conventional cardiovascular risk factors (body mass index, mean arterial blood pressure, total cholesterol and smoking status). e Peak endothelial dependent responses to acetylcholine (ACh) in those with and without diabetes adjusted for age, sex, conventional cardiovascular risk factors and HbA1c. f Peak endothelial independent response to sodium nitroprusside (SNP) in those with and without diabetes adjusted for age, sex, conventional cardiovascular risk factors and HbA1c. DM participants recruited with diabetes (including those diagnosed during screening); No DM participants recruited with no clinical history of diabetes and no elevated HbA1c at screening