Figure 1.

Protective effect of MgIG treatment against chronic plus binge ethanol feeding-induced hepatic injury. (a) Experimental design of liquid control or ethanol diet feeding and drug treatments. Mice were treated as described in (a); liver injury was assessed by measuring serum alanine aminotransferase (ALT) levels (b) and aspartate aminotransferase (AST) levels (c). (d) Representative H&E staining. Arrows indicate macrovesicular and microvesicular steatosis. (e) Hepatic triglyceride (TG) levels were measured. Values represent means ± SEM. ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001.