Table 4.

Adjusted average difference of insulin secretion and insulin sensitivity according to H. pylori status at baseline in participants at risk for diabetes in the Diabetes and Prevention Program (DPP) study.

	H. pylori status *		P-value
	Negative	Positive
Insulin sensitivity index, [(µU/mL)*( mg/dL)]-1 †	(reference)	−0.02 (−0.10, 0.05)	0.53
Corrected insulin response, CIR (µU/mL)/(mg/dL)2 †	(reference)	0.08 (−0.01, 0.17)	0.08
Disposition index-like measure from OGTT (LN(CIR) * LN (Insulin sensitivity index))	(reference)	−0.12 (−0.29, 0.05)	0.17

Results are presented by H. pylori status; average difference between groups was calculated from a multivariate linear regression model; all models are adjusted for matching factors (age [years], sex [male or female], race/ethnicity [Non-Hispanic White vs. Other], DPP intervention arm [lifestyle or placebo] and length of follow up), BMI at baseline, smoking status (never, past, or currently smoking), alcohol consumption (g/day), self-reported physical activity (MET-hours per week).

^†Dependent variable log transformed