Table 3.
Variables | Univariate | Multivariate | ||
---|---|---|---|---|
Odds ratio for frailty (95% CI) | P | Adjusted odds ratio for frailty (95% CI) | P | |
Frailty defined by Fried frailty phenotype | ||||
Female gender | 1.19 (0.80–1.75) | 0.39 | – | – |
Age | 1.08 (1.06–1.11) | <0.001 | 1.07 (1.05–1.10) | <0.001 |
Low education (not finish high school) | 1.94 (1.29–2.93) | 0.01 | 1.58 (1.01–2.46) | 0.04 |
Poor reported nutritional status | 3.68 (1.85–7.29) | <0.001 | 2.96 (1.43–6.11) | 0.01 |
Cardiovascular diseases | 1.57 (1.07–2.30) | 0.02 | 1.76 (1.16–2.67) | 0.01 |
Hypertension | 1.01 (0.68–1.49) | 0.97 | – | – |
Diabetes mellitus | 1.16 (0.72–1.74) | 0.63 | – | – |
Chronic pulmonary diseases | 1.27 (0.72–2.24) | 0.41 | – | – |
Renal impairment (GFR < 60 ml/min/1.73 m2) | 3.58 (2.02–6.33) | <0.001 | – | – |
Cancer | 1.87 (0.69–5.08) | 0.22 | – | – |
Osteoarthritis | 1.44 (0.93–2.22) | 0.10 | – | – |
Anemia | 1.51 (0.96–2.38) | 0.08 | – | – |
Living alone | 0.91 (0.23–3.70) | 0.90 | – | – |
Frailty defined by REFS | ||||
Female gender | 1.68 (1.12–2.52) | 0.01 | – | – |
Age | 1.06 (1.04–1.09) | <0.001 | 1.05 (1.03–1.08) | <0.001 |
Low education (not finish high school) | 2.71 (1.74–4.22) | <0.001 | 2.18 (1.37–3.46) | 0.001 |
Poor reported nutritional status | 5.66 (2.78–11.54) | <0.001 | 4.51 (2.15–9.44) | <0.001 |
Cardiovascular diseases | 0.85 (0.57–1.26) | 0.41 | – | – |
Hypertension | 0.82 (0.55–1.22) | 0.32 | – | – |
Diabetes mellitus | 1.17 (0.75–1.84) | 0.49 | – | – |
Chronic pulmonary diseases | 1.09 (0.60–1.96) | 0.78 | – | – |
Renal impairment (GFR < 60 ml/min/1.73 m2) | 2.16 (1.22–3.81) | 0.01 | – | – |
Cancer | 1.69 (0.62–4.64) | 0.31 | – | – |
Osteoarthritis | 1.19 (0.76–1.86) | 0.44 | – | – |
Anemia | 1.71 (1.07–2.75) | 0.03 | – | – |
Living alone | 4.41 (1.09–17.89) | 0.04 | – | – |
Only variables that had a P-value <0.20 in univariate regression were entered into multiple regression model
REFS Reported Edmonton Frail Scale, GFR glomerular filtration rate, CI confidence interval