Table 1.

Description of the image acquisition parameters used to compare five computed tomography imaging protocols. Each set was acquired in a single breath hold with the control protocol (X_control) acquired first followed by two target protocols (X₁, X₂). All images were reconstructed with the same iterative reconstruction kernel, same field of view diameter, and same voxel resolution

Scan ID	Scan description	Quality reference mAs	kV	Tube current modulation (“CARE Dose”)	Pitch	Exp. time
Control variability	Control	118	120	On	1	0.5
	SPIROMICS w TCM	118	120	On	1	0.5
	SPIROMICS w TCM	118	120	On	1	0.5
No‐TCM	Control	118	120	On	1	0.5
	SPIROMICS	110	120	Off	1	0.5
	SPIROMICS	110	120	Off	1	0.5
Low‐dose	Control	118	120	On	1	0.5
	Low‐dose chest	52	110	On	1.2	0.5
	Low‐dose chest	52	110	On	1.2	0.5
Ultralow‐dose	Control	118	120	On	1	0.5
	Ultralow‐dose	10	120	On	1	0.5
	Ultralow‐dose	10	120	On	1	0.5
Tin‐filtered ultralow‐dose	Control	118	120	On	1	0.5
	Sn ultralow‐dose	97	Sn100	On	1.2	0.5
	Sn ultralow‐dose	97	Sn100	On	1.2	0.5