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. Author manuscript; available in PMC: 2018 Feb 23.
Published in final edited form as: J Med Chem. 2017 Jan 27;60(4):1591–1597. doi: 10.1021/acs.jmedchem.6b01166

Figure 6.

Figure 6

Mechanism of action of 19. Inhibition constants (Ki) were determined by titrating (A) 3-PG and (B) NAD+ at four concentrations of 19 (in nanomolar). (C) Washout experiment of 19.