Table 5.
SNP seta | Omnibus | Haplotype | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||||
1 | 2 | 3 | STAT | p | Haplotype | Frequency | OR | STAT | p | ||
rs12976518 | rs10445572 | rs2377324 | 10.400 | 0.01530 | A | A | G | 0.278 | 0.548 | 7.040 | 0.00796 |
G | G | A | 0.386 | 1.610 | 6.520 | 0.01070 | |||||
G | A | A | 0.086 | 1.510 | 1.660 | 0.19800 | |||||
A | A | A | 0.241 | 0.816 | 0.860 | 0.35400 | |||||
rs10445572 | rs2377324 | rs2240672 | 9.780 | 0.02050 | A | G | A | 0.274 | 0.552 | 6.780 | 0.00924 |
G | A | A | 0.048 | 1.120 | 0.070 | 0.79200 | |||||
G | A | G | 0.344 | 1.610 | 6.530 | 0.01060 | |||||
A | A | G | 0.324 | 0.992 | 0.002 | 0.96800 | |||||
rs2377324 | rs2240672 | rs345409 | 8.370 | 0.03900 | G | A | G | 0.268 | 0.559 | 6.390 | 0.01150 |
A | A | G | 0.050 | 1.070 | 0.029 | 0.86500 | |||||
A | G | G | 0.138 | 1.420 | 2.010 | 0.15600 | |||||
A | G | A | 0.530 | 1.300 | 2.100 | 0.14700 | |||||
rs2240672 | rs345409 | rs11883302 | 7.410 | 0.19200 | A | G | G | 0.246 | 0.584 | 4.920 | 0.02660 |
G | G | G | 0.096 | 1.100 | 0.096 | 0.75600 | |||||
G | A | G | 0.019 | 1.720 | 0.637 | 0.42500 | |||||
A | G | A | 0.073 | 0.788 | 0.387 | 0.53400 | |||||
G | G | A | 0.047 | 1.700 | 1.780 | 0.18200 | |||||
G | A | A | 0.513 | 1.270 | 1.650 | 0.19900 |
Key: SNP, single nucleotide polymorphism.
SNP(s) most strongly associated with AD are bolded and italicized, and the most significant haplotype is highlighted in gray.