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. Author manuscript; available in PMC: 2018 Aug 1.

Published in final edited form as: Neurobiol Aging. 2017 May 3;56:150–158. doi: 10.1016/j.neurobiolaging.2017.04.018

Table 5.

Haplotypes analysis for MARK4 and Alzheimer’s disease: 3-SNP window

SNP set^a			Omnibus		Haplotype

1	2	3	STAT	p	Haplotype			Frequency	OR	STAT	p
rs12976518	rs10445572	*rs2377324*	10.400	0.01530	A	A	G	0.278	0.548	7.040	0.00796
					G	G	A	0.386	1.610	6.520	0.01070
					G	A	A	0.086	1.510	1.660	0.19800
					A	A	A	0.241	0.816	0.860	0.35400
rs10445572	*rs2377324*	rs2240672	9.780	0.02050	A	G	A	0.274	0.552	6.780	0.00924
					G	A	A	0.048	1.120	0.070	0.79200
					G	A	G	0.344	1.610	6.530	0.01060
					A	A	G	0.324	0.992	0.002	0.96800
*rs2377324*	rs2240672	rs345409	8.370	0.03900	G	A	G	0.268	0.559	6.390	0.01150
					A	A	G	0.050	1.070	0.029	0.86500
					A	G	G	0.138	1.420	2.010	0.15600
					A	G	A	0.530	1.300	2.100	0.14700
rs2240672	rs345409	rs11883302	7.410	0.19200	A	G	G	0.246	0.584	4.920	0.02660
					G	G	G	0.096	1.100	0.096	0.75600
					G	A	G	0.019	1.720	0.637	0.42500
					A	G	A	0.073	0.788	0.387	0.53400
					G	G	A	0.047	1.700	1.780	0.18200
					G	A	A	0.513	1.270	1.650	0.19900

Key: SNP, single nucleotide polymorphism.

^a

SNP(s) most strongly associated with AD are bolded and italicized, and the most significant haplotype is highlighted in gray.