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. Author manuscript; available in PMC: 2017 Sep 19.
Published in final edited form as: Annu Rev Cell Dev Biol. 2009;25:1–19. doi: 10.1146/annurev.cellbio.042308.113341

Figure 15.

Figure 15

A single Cajal body from a Xenopus germinal vesicle visualized by (a) differential interference contrast and (b–d ) confocal laser scanning microscopy.

(b) Stained with an antibody against coilin.

(c) Stained with an antibody against the Sm epitope, now known to be symmetric dimethylarginine.

(d ) Merge of (b) and (c). These images show three speckles on the surface of the Cajal body and one inside. The unstained object to the lower left of the Cajal body in (a) is a free nucleolus. Modified from Bellini & Gall (1998) with permission from Molecular Biology of the Cell.