Table 1.
DNA/PNA | Sequencea | # of γ units |
---|---|---|
DNA 1 | d(GGGTTAGGGTTAGGGT) | N/A |
PNA 1 | Ac-HN -TGGGT-Lys-CONH2 | 0 |
PNA 2 | Ac-HN -TGGRGT-Lys-CONH2 | 1 |
PNA 3 | Ac-HN -TGRGGRT-Lys-CONH2 | 2 |
PNA 4 | Ac-HN-TGGGT-Lys-CONH2 | 1 |
PNA 5 | Ac-HN-TGGGT-Lys-CONH2 | 2 |
PNA 6 | Ac-HN-TGGGT-Lys-CONH2 | 3 |
PNA oligomers are written from N terminus to C terminus. The LKγ-PNA-G-RGD monomers (GR) are bold and underlined for clarity, LKγ-PNA-G monomers (G) have a free amine on the side chain.