Extended Data Figure 9. Studies in T- and B-cell-deficient mice.

a, Measurement of lymphocyte subsets in the blood of +/+ and Rag2^−/− mice (multiple two-tailed unpaired t-tests with P value adjusted by the Holm–Šídák method with α set to 5%). b, Experimental metastasis assay using B16-F10 cells in +/+ and Rag2^−/− female mice (Mann–Whitney test). Symbols represent individual mice, horizontal bars represent mean; data shown are representative of three independent experiments.