Table 4.

Literature review of serial staged excision for melanoma in situ.

Staged Excision Studies	Recurrence	Time to Recurrence	Follow-up Duration
Walling et al. [15]	3/41 (7.3%)	24 ± 13 months	96 ± 43.6
			(range 60–240 months)
Bub et al. [16]	2/55 (3.6%)	Not reported	57 months
			(range 9–139 months)
Huilgol et al. [17]	2/125 (1.6%)	12, 40 months	38 ± 25
Johnson et al. [18]	0/35 (0%)	NA	Not reported
Hill and Gramp. [19]	1/38 (2.6%)	10 months	25 months (range 10–48 months)
Anderson et al. [20]	1/150 (0.67%)	<5 years, not defined	Not reported
Agarwal-Antal et al. [21]	0/93 (0%)	Not reported	Not reported
			“4 years after first patient”
Malhotra et al. [22]	4/109 (3.7%)	12–40 months	32±26 months
Mahoney et al. [23]	0/11 (0%)	NA	4.7 months (range 1–13 months)
Jejurikar et al. [24]	0/51 (0%)	NA	31 months (range 15–45 months)
Bosbous et al. [25]	1/59 (1.7%)	Not reported	2.2 years (range 0–10.2 years)
Lee and Ryman [26]	3/31 (9.7%)	Mean 4 years	42 months
Joyce et al. [27]	9/410 (2.2%)	Mean 29.6 months (range 8–47 months)	23 months (range 1–65 months)
de Vries et al. [28]	4/100 (4%)	37–77 months	Mean 60 months
Patel et al. [29]	1/21(4.76%)	2 years	Not reported
Lawrence et al. [30]	4/56 (12%)	Mean 4.4 years (range 0.6–7.4 years)	Minimum 5 years (range 5–9.6 years)
Gaudy-Marqueste et al. [31]	0/20 (0%)	48 months	Mean 25.36 months (range 0–72 months)
Möller et al. [32]	0/49 (0%)	NA	Median 14 months (range 1–36 months)
Garcia and Jiang	0/29 (0%)	NA	Mean 31.5 months (range 12–58 months)