Skip to main content
. Author manuscript; available in PMC: 2018 Jul 18.
Published in final edited form as: Acc Chem Res. 2017 Jul 6;50(7):1577–1586. doi: 10.1021/acs.accounts.7b00175

Figure 2.

Figure 2

Thiopeptides targeting EF-Tu. (A) Structure of GE2270A with tailoring modifications highlighted; Thz, thiazole. (B-D) Different views of GE2270A (PDB ID 2C77)11 bound to EF-Tu. E) Structure of thiomuracin I, and F) X-ray structure bound to EF-TU (PDB ID 4G5G).78