Table 2.
Detection rates and interquartile ranges for chemokines/cytokines based on HPgV RNA status and HPGV genotype.
| Cytokine/chemokine | Detection rate (%) | HPgV RNA negative | HPgV RNA positive | HPgV RNA positive versus negative | HPgV genotype 1 | HPgV genotype 2 | HPgV genotype 1 versus genotype 2 |
|---|---|---|---|---|---|---|---|
| N = 80 | N = 70 | P value | N = 28 | N = 42 | P value | ||
| IL-2 | 55% | 0.8 (0–1.4) | 0.6 (0–5.5) | 0.138 | 1.5 (0–5.5) | 0 (0–5.1) | 0.513 |
| IL-4 | 72% | 10.4 (3.3–26.6) | 0 (0–10.9) | <0.001 | 1.7 (0–7.7) | 0 (0–15.3) | 0.702 |
| IL-7 | 35% | 0 (0–0) | 3.7 (0–8.7) | <0.001 | 2.1 (0–8.2) | 5.0 (0–9.1) | 0.494 |
| IL-8 | 100% | 630 (218–1892) | 155 (45.6–648) | <0.001 | 159 (61.5–2609) | 155 (44.2–626) | 0.615 |
| IL-10 | 87% | 8.0 (4.2–14.2) | 7.0 (3.7–12.2) | 0.403 | 5.8 (2.0–9.2) | 8.5 (5.0–13.6) | 0.092 |
| IL-12p70 | 50% | 0 (0–0) | 1.7 (0.7–6.6) | <0.001 | 2.3 (1.0–4.8) | 1.5 (0.7–7.2) | 0.341 |
| IL-13 | 18% | 0 (0–0) | 0 (0–1.8) | 0.001 | 0 (0–1.1) | 0 (0–4.1) | 0.433 |
| IFNγ | 85% | 1.9 (1.3–5.2) | 5.1 (1.2–16.0) | 0.013 | 2.9 (0–9.4) | 6.8 (1.9–22.8) | 0.036 |
| TNFα | 100% | 23.3 (14.6–34.0) | 23.9 (14.9–30.3) | 0.799 | 22.9 (14.2–29.9) | 26.2 (14.9–33.7) | 0.787 |
| IP-10 | 100% | 1561 (1100–2063) | 1105 (721–1505) | <0.001 | 950 (616–1323) | 1240 (898–1724) | 0.061 |
| MIP-1α | 95% | 53.0 (26.4–113.9) | 52.2 (29.2–93.1) | 0.758 | 52.7 (35.8–90.2) | 48.9 (23.3–98.6) | 0.749 |
| MIP-1β | 98.7% | 99.7 (60.1–148.0) | 82.4 (63.01–146) | 0.414 | 92.3 (72.1–144) | 75.5 (57.7–146) | 0.164 |
| TGF-β1 | 93.3% | 29644 (25714–36105) | 628 (228–1036) | <0.001 | 628 (228–993) | 556 (372–1036) | 0.957 |
Statistical evaluation was based on log-transformed values since the values were not normally distributed; however, to demonstrate the range of cytokine/chemokine measures, the absolute values are shown.