Figure 4. Schematic showing breeding strategies to determine whether the occurrence of Fak floxed allele recombination is at or after zygote stage.

Male mice heterozygous for Dermo1-Cre transgene were mated with female mice homozygous for Fak floxed allele. The table below the scheme shows the expected as well as the observed genotype distribution. The numbers of animals per total number of animals (n=26) is shown in parentheses.