Figure 5. Schematic showing breeding strategies and Fak gene deletion using female mice as Dermo1-Cre carrier.

Female mice heterozygous for both the Fak floxed allele and the Dermo1-Cre transgene were mated with male mice homozygous for Fak floxed allele. The table below the scheme shows the expected as well as the observed genotype distribution. The numbers of animals per total number of animals (n=123) is shown in parentheses. The data were obtained from 9 different female breeders.