Table 4.

Hierarchical logistic regression estimates of childhood maltreatment predicting cannabis dependence at 21-year, Brisbane, Australia.

Childhood maltreatment	Category	Unadjusted OR (95%CI)	Adjusted OR (95%CI)
		Model 1	Model 2	Model 3	Model 4
Any maltreatment	No	1	1	1
Any maltreatmenta,b	Yes	2.69 (1.58–4.61)****	2.48 (1.43–4.30)***	2.47 (1.43–4.29)***	–
Sexual abuse	Yes	1.12 (0.33–3.77)	1.21 (0.35–4.14)	1.22 (0.36–4.19)	1.30 (0.38–4.47)
Physical abuse	Yes	3.03 (1.39–6.58)**	2.79 (1.26–6.18)*	2.72 (1.23–6.01)*	2.81 (1.27–6.22)*
Emotional abuse	Yes	2.70 (1.26–5.81)*	2.39 (1.09–5.20)*	2.36 (1.80–5.15)*	2.44 (1.12–5.33)*
Neglect	Yes	2.93 (1.22–7.01)**	2.54 (1.05–6.19)*	2.57 (1.05–6.25)*	2.68 (1.09–6.52)*

^aAny childhood maltreatment included one or more combination of neglect, sexual, physical or emotional abuse.

^bModel did not adjust for other forms of childhood maltreatment.

Model 1: Unadjusted child maltreatment and cannabis dependence.

Model 2: Model 1 + gender at birth, maternal age at pregnancy, maternal smoking at pregnancy and 6 months postpartum and family poverty over the first 5 years of age.

Model 3: Adjusted for Models 1 + 2 + educational level and marital status at 21 years.

Model 4: Adjusted for Models 1 + 2 + 3 + any substantiated childhood maltreatment excluding the variable of interest to avoid the effect of overlapping maltreatment.

^*p <0.05;

^**p <0.01;

^***p <0.01;

^****p <0.0001.