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. Author manuscript; available in PMC: 2018 Sep 18.
Published in final edited form as: Chemistry. 2017 Jul 27;23(52):12690–12703. doi: 10.1002/chem.201702117

Figure 7.

Figure 7

Bicyclic peptide libraries synthesized by mRNA display and SICLOPPS. a) Scheme showing the key features of the mRNA display technology; b) bicyclization of mRNA displayed peptides by the method of Sako et al.;[36] c) bicyclization of mRNA displayed peptide library by the method of Hacker et al.;[37] and d) bicyclization of SICLOPPS-synthesized peptides by the method of Bionda and Fusan.[39]