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. 2017 Sep 18;8:569. doi: 10.1038/s41467-017-00408-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Regional association plot including both genotyped and imputed SNPs at 11q22.2. a Plotted are the regional association results from the meta-analysis of discovery and replication cohorts (−log10 transformed P values) and the recombination rate. SNPs are colored to reflect pairwise LD (r ²) with the most significantly associated SNP. The most significant SNP is shown in purple. The tracks of b CHROMHMM (Celline: HepG2, HSMM, K562, GM12878), c wgEncodeRegTfbsClusteredV3 and tfbsConsSites annotation are plotted on the bottom