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. 2017 Sep 18;7:11767. doi: 10.1038/s41598-017-12227-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Tumor impedance measurement during MHIRE treatment. Impedance trends were taken from the voltage probe and current-viewing resistor readings over the 90 pulses applied. Each data point represents an average impedance reading of 4 to 5 tumors for that pulse. IRE parameters: 100 µs pulse width, 90 pulses, frequency of 1 Hz and applied electric fields of 1.5 kV/cm (left), 2 kV/cm (middle) and 2.5 kV/cm (right). Standard deviations for the 1^st, 10^th and 80^th pulses are indicated with error bars.