Table 1.
Patient characteristic | Total | Number | % |
---|---|---|---|
Total patient | 1004 | ||
Median age(range) | 1004 | 58(26–82) | |
Age | 1004 | ||
≤58 | 518 | 51.6 | |
>58 | 486 | 48.4 | |
Gender | 1004 | ||
Male | 706 | 70.3 | |
Female | 298 | 29.7 | |
TNM Stage | 999 | ||
IIIA | 81 | 8.1 | |
IIIB | 293 | 29.3 | |
IV | 625 | 62.6 | |
ECOG PS | 990 | ||
0–1 | 904 | 91.3 | |
2 | 86 | 8.7 | |
Histological Type | 1004 | ||
Adenocarcinoma | 632 | 62.9 | |
Squamous Cell Carcinoma | 221 | 22.0 | |
Adenosquamocarcinoma | 20 | 2.0 | |
Othersa | 131 | 13.1 | |
Smoking Statusb | 1000 | ||
Never smoker | 425 | 42.5 | |
Ever smoker | 575 | 57.5 | |
Chemotherapy Regimens | 1004 | ||
Platinum-navelbine | 316 | 31.5 | |
Platinum-gemcitabine | 239 | 23.8 | |
Platinum-paclitaxel | 313 | 31.1 | |
Platinum-docetaxel | 87 | 8.7 | |
Others platinum combinations | 49 | 4.9 | |
Objective Response | 975 | ||
CR | 1 | 0.1 | |
PR | 176 | 18.1 | |
SD | 610 | 60.0 | |
PD | 188 | 19.3 | |
Severe gastrointestinal toxicity | 964 | 80 | 8.3 |
Severe hematological toxicity | 969 | ||
Anemia | 944 | 29 | 3.1 |
Neutropenia | 935 | 115 | 12.3 |
Thrombocytopenia | 950 | 34 | 3.6 |
Median Time to outcomes (month) | 972 | ||
PFS | 896 | 9.1 | |
OS | 972 | 19.3 |
ECOG PS, Eastern Cooperative Oncology Group performance status; TNM, tumor-node metastasis; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; PFS, progression-free survival (months); OS, overall survival (months).
aOther carcinomas included mixed cell or undifferentiated carcinoma.
bNonsmokers were defined as those who had smoked <1 cigarette per day and for <1 year in their lifetime.