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. 2017 Sep 18;7:11751. doi: 10.1038/s41598-017-11843-4

Table 3.

MIC50 of CyC17 against M. tb mc26230 overexpression strains.

Overexpression strains MIC50 (µM) MIC50 ratio mutant/WT
M. tb mc26230 WT 0.55 ± 0.023‡,† 1.00
M. tb mc26230-empty vector 0.52 ± 0.010 0.95
M. tb mc26230-Ag85A 0.55 ± 0.014 1.00
M. tb mc26230-Ag85C 0.54 ± 0.009 0.98
M. tb mc26230-Rv0183 0.44 ± 0.013 0.80
M. tb mc26230-LipH 0.72 ± 0.020*,‡ 1.31
M. tb mc26230-TesA 0.52 ± 0.012 0.95
M. tb mc26230-HsaD 1.20 ± 0.026*,† 2.18

aExperiments were performed as described in Materials and Methods. MIC50: compound minimal concentration leading to 50% growth inhibition. Values are mean of at least two independent assays performed in triplicate (CV% < 5%). MIC50 values with a commun symbol (*,,) are significantly different (p-value < 0.001; ANOVA followed by Fisher’s test).