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. 2017 Sep 18;7:11750. doi: 10.1038/s41598-017-10507-7

Table 2.

Functional annotation of the risk SNPs associated with WM microstructural abnormalities in schizophrenia.

CHR POS (hg19) SNP Chromatin states Motifs changed Genes Positional RegulomeDB
annotation
8 1304999 kgp5929161 Enhancer DMRT2 20 kb 3′ of DLGAP2 NA TF binding or DNase peak
(rs62487409) (ESC, iPSC)
14 20871645 rs8009925 Enhancer 5 altered motifs TEP1 intronic TF binding or DNase peak
(iPSC)
20 50083574 rs193091397 Enhancer AhR,CHOP::CEBPalpha NFATC2 intronic No Data
(Blood & T-cell) NRSF
2 202531547 rs7559992 Enhancer 6 altered motifs MPP4 intronic Others
(NH-A Astrocytes Primary Cells)
10 109575094 rs10509852 Enhancer RXR::LXR 400kb 5′ of SORCS1 NA TF binding or DNase peak
(ES-deriv, HSC & B-cel)
2 237497237 rs11901793 Enhancer 5 altered motifs 6.2 kb 3′ of CXCR7 NA TF binding or DNase peak
(ES-deriv, Neurosph)