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. 2017 Sep 18;3:31. doi: 10.1038/s41537-017-0035-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Uptake of cystine by OPCs was evaluated after 15 min (a) and 30 min (b). Three conditions were compared: without shRNA (black), transduced with a scrambled shRNA (gray), transduced with GCLC knock-down (white). Background level of cystine uptake was evaluated in the presence of glutamate (red). Data are represented as mean ± standard error of the mean (n = 4 per group); *p-value < 0.05