Table 1.
Clinical characteristics of the patients at the beginning of the study
| Parameter | Spironolactone group (n = 22) | Control group (n = 15) | p |
|---|---|---|---|
| Age (years) | 54.57 ± 13.78 | 51.14 ± 18.72 | 0.70 |
| BMI (kg/m2) | 25.16 ± 3.58 | 24.05 ± 4.42 | 0.61 |
| Time on PD at the onset of the study (months) | 25.28 ± 9.46 | 20.42 ± 10.69 | 0.38 |
| Hemoglobin concentration (g/dl) | 11.45 ± 0.97 | 11.55 ± 1.39 | 0.65 |
| Serum calcium (mmol/l) | 2.29 ± 0.24 | 2.28 ± 0.13 | 0.28 |
| Serum phosphorus (mmol/l) | 1.60 ± 0.30 | 1.75 ± 0.58 | 0.55 |
| PTH (pg/ml) | 306.00 (125.0;759.0) | 376.00 (98.0;805.0) | 0.22 |
| Serum albumin (g/dl) | 4.17 ± 0.23 | 3.99 ± 0.20 | 0.60 |
| Urine volume (ml/day) | 914.28 ± 94.49 | 878.57 ± 191.17 | 0.66 |
| UF volume (ml/day) | 872.85 ± 96.55 | 910 ± 134.90 | 0.56 |
| PET | |||
| H | 7 | 5 | 0.14 |
| HA | 12 | 8 | 0.34 |
| LA | 3 | 2 | 0.54 |
| L | 0 | 0 |
Normally distributed data are expressed as mean ± SD, and not normally distributed data are expressed as median ± IQR
BMI body mass index, PET peritoneal equilibration test, UF ultrafiltration, PTH parathormone, PD peritoneal dialysis; H high, HA high average, LA low average, L low