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. 2017 Sep 14;11:63. doi: 10.3389/fncir.2017.00063

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Copyright © 2017 Datta and Oliver.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Application of U0126 into the PPT suppresses selective REM sleep deprivation-induced REM sleep homeostatic pressure. This effect was observed during the 3-h sleep-wake recording session that immediately followed bilateral microinjections of U0126. (A) Bars represent number (mean ± SE) of REM sleep episodes. (B) Bars represent total percentages of time (mean ± SE) spent in REM sleep. (C) Bars represent percentages of time spent in wakefulness. (D) Bars represent percentages of time spent in NR. Post hoc tests (Bonferroni’s multiple comparisons test): triangle represents the comparison with vehicle control + REM sleep control (VC + RSC) and asterisk represents the comparison with vehicle control + selective REM sleep deprivation (VC + RSD). ∆p < 0.05; ∆∆∆ or ***p < 0.001.