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. 2017 Sep 14;11:63. doi: 10.3389/fncir.2017.00063

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Copyright © 2017 Datta and Oliver.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Working model depicting molecular steps in the PPT cholinergic neurons involved in the regulation of RSHD. Arrows: normal activating effects on the target molecule. Dotted arrows: loss of activating effects on the target molecule due to application of U0126 (ERK1/2 activation inhibitor).