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. 2017 Sep 14;8:697. doi: 10.3389/fphys.2017.00697

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Copyright © 2017 Wei, Thomas, Hatch, Hu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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μCT analysis of bone parameters of cranial vault bones (frontal and parietal bone). (A) Diagram of mouse skull at dorsal view showing the measured area in frontal bone (F) and parietal bone (P). (B–F) μCT analysis of bone parameters (thickness, bone volume/tissue volume[BV/TV], bone volume[BV], bone mineral density[BMD], and tissue mineral density[TMD], respectively) in frontal and parietal bone with age. ^*Represents significant change between indicated data point and immediate earlier time point; ^#Represents significant change between indicated data points (Tukey's multiple comparison test, p < 0.05).