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. 2017 Sep 14;8:651. doi: 10.3389/fphar.2017.00651

Table 3.

Assessment of histopathological scores.

Grade Extent of inflammation Infiltration neutrophils+ lympho-histiocytes Extent of crypt damage Crypt abscesses Sub-mucosal edema Loss of goblet cells Reactive epithelial hyperplasia
0 None None None None None None None
1 Mucosa Focal Basal one third Focal Focal Focal Focal
2 Mucosa+ submucosa Multifocal Basal two thirds Multifocal Multifocal Multifocal Multifocal
3 Mucosa+submucosa+ muscle layer Diffuse Entire crypt damage Diffuse Diffuse Diffuse
4 Transmura Crypt damage+ulceration