Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 14;8:647. doi: 10.3389/fphar.2017.00647

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Zuo, Zuo, Zheng, Wang, Zhou, Chen and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Immunohistochemistry. α-SMA (A) immunostaining for detecting plaque SMC content showed a significant reduction in PAR-2^-/- mice, as compared to the controls. Immunohistochemistry staining with antibody against Mac-2 (B), which demonstrates the presence of macrophages within the atherosclerotic lesion, showed a significant reduction in PAR-2^-/- mice. Staining for MMP-9 (C) showed a significant reduction in PAR-2^-/- mice. Immunohistochemistry staining with antibody against CD-31 (D), which is regarded as evidence of neovascularization, showed a significant reduction in PAR-2^-/- mice, as compared to the controls. (C,D) Magnified the shoulder regions of atherosclerotic plaques in the vessel. The arrows show positive stained areas within the atherosclerotic lesions. Data represent mean ± SD. ^∗P < 0.05.