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Baicalin prevents chronic-binge ethanol-induced liver injury by modulating NRF2 and its target genes HO-1 and NQO1. (a) Western blot analyses of nuclear extracts of NRF2 along with loading control histone H3. Hepatic mRNA of HO-1 and NQO1 was analyzed by real-time PCR. The results are expressed as fold change relative to the pair-fed group. Values represent means ± SEM and n = 6/group. ∗P < 0.05 versus pair-fed group, #P < 0.05 versus EtOH group.
