Scheme 3. Scope of the palladium-catalyzed difluoromethylation of heteroaryl chlorides. ^aReaction conditions: heteroaryl chlorides (0.5 mmol), (SIPr)Ag(CF₂H) 2 (0.65 mmol), Pd(dba)₂ (5 mol%), DPEPhos (10 mol%) in toluene (2.5 mL) at 80 °C for 18 h; ^bisolated yields.