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. 2017 Jul 17;231(4):634–637. doi: 10.1111/joa.12658

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© 2017 The Authors. Journal of Anatomy published by John Wiley & Sons Ltd on behalf of Anatomical Society

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Electron microscopy image of the structure and 3D reconstructions of the stack. (A) An image from the SBFSEM showing the syncytiotrophoblast (STB), the erythrocytes (RBC) and the main protruding erythrocyte (arrow). (B) The segmented structure showing the surface of the syncytiotrophoblast and the protruding erythrocytes (arrows) (Supporting Information Video S1b). (C) Segmentation of the largest protruding erythrocyte (red) pushing through the syncytiotrophoblast (blue) in two places (arrows). (Supporting Information Video S1c).