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Influence of formulation variables on EE (%) of niosomes prepared by thin-film hydration method (n = 3, mean ± SD
| Formula | L/D | Span/cholesterol | Drug Concentration (mg/mL) | EE (%) |
|---|---|---|---|---|
| F1 | 10 | 70/30 | 0.5 | 1.8 ± 0.3 |
| F2 | 20 | 70/30 | 0.5 | 5.6 ± 0.6 |
| F3 | 30 | 70/30 | 0.5 | 23.5 ± 0.5 |
| F5 | 40 | 70/30 | 0.5 | 24.5 ± 0.7 |
| F6 | 30 | 80/20 | 0.5 | 18.1 ± 0.8 |
| F7 | 30 | 60/40 | 0.5 | 27.5 ± 0.5 |
| F8 | 30 | 50/50 | 0.5 | 24.3 ± 0.7 |
| F9 | 30 | 60/40 | 1 | 20.2 ± 0.9 |
| F10 | 30 | 60/40 | 2.5 | 7.7 ± 2.0 |
