Table 1.
Biodistribution of 90Y-DOTA-Rituximab in normal mice
| Tissue |
4 h
|
24 h
|
72 h
|
|---|---|---|---|
| mean±SD (n=3) | |||
| Blood | 32.78 ± 0.28 | 10.5 ± 1.34 | 2.96 ± 0.09 |
| Lungs | 34.69 ± 1.21 | 8.92 ± 0.13 | 4.91 ± 0.9 |
| Heart | 21.5 ± 2.07 | 5.71 ± 1.23 | 3.78 ± 0.34 |
| Liver | 25.32 ± 1.16 | 19.13 ± 3.3 | 14.13 ± 5.9 |
| Spleen | 28.67 ± 3.07 | 9.34 ± 1.49 | 18.76 ± 3 |
| Stomach | 2.40 ± 0.28 | 1.71 ± 0.6 | 0.62 ± 0.13 |
| Small intestine | 3.40 ± 0.27 | 1.85 ± 0.2 | 0.97 ± 0.3 |
| Large intestine | 4.51 ± 0.91 | 3.35 ± 0.9 | 2.12 ± 0.3 |
| Kidneys | 17.73 ± 0.87 | 8.2 ± 1.9 | 5.3 ± 0.58 |
| Bone | 6.01 ± 0.07 | 5.13 ± 0.17 | 4.5 ± 0.5 |